Publications

C. Bressan, M. Snapyan, M. Snapyan, J. Klaus, F. di Matteo, S. P. Robertson, B. Treutlein, M. Parent, S. Cappello and A. Saghatelyan
Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia
EMBO Mol Med, doi: 10.15252/emmm.202216908. (2023).external pagearticlecall_made

C. Li, J. S. Fleck, C. Martins-Costa, T. R. Burkard, J. Themann, M. Stuempflen, A. M. Peer, Á. Vertesy, J. B. Littleboy, C. Esk, U. Elling, G. Kasprian, N. S. Corsini, B. Treutlein and J. A. Knoblich
Single-cell brain organoid screening identifies developmental defects in autism
Nature, 621, 373-380. (2023).external pagearticlecall_made

 

J. S. Fleck, J. G. Camp and B. Treutlein
What is a cell type?
Science, 381, 6659, 733-734. (2023).external pagearticlecall_madeexternal pagecall_made

P. Wahle, G. Brancati, C. Harmel. Z. He, G. Gut, J.S. Castillo, A. Santos, Q. Yu, P. Noser, J. S. Fleck, B. Gjeta, D. Pavlinić, S. Picelli, M. Hess, G. W. Schmidt, T. Lummen, Y. Jou, P. galliker, D. Goldblum, M. Balogh, C. S. Cowan, H. P. N. Scholl, B. Roska, M. Renner, L. Pelkmans, B. Treutlein and J. G. Camp
Multimodal spatiotemporal phenotyping of human retinal organoid development
Nature biotechnology, DOI: https://doi.org/10.1038/s41587-023-01747-2 . (2023).external pagearticlecall_made

P. Cahan and B. Treutlein
A conversation with ChatGPT on the role of computational systems biology in stem cell research
Stem Cell Reports, 18, 1, 1-2. (2023).external pagearticlecall_made

J. G. Camp and B. Treutlein
Human brain organoids influence rat behaviour
Nature, Oct; 610 (7931):265-266. doi: 10.1038/d41586-022-02977-1. (2022).external pagearticlecall_made
 

J. S. Fleck, S. M. J. Jansen, D. Wollny, F. Zenk, M. Seimiya, A. Jain, R. Okamoto, M. Santel, Z. He, J. G. Camp and B. Treutlein
Inferring and perturbing cell fate regulomes in human brain organoids
Nature, 377, DOI: https://doi.org/10.1038/s41586-022-05279-8 . (2022).external pagearticlecall_made


K. Lust, A. Maynard, T Gomes, J. S. Fleck,  J. G. Camp, E. M. Tanaka and B. Treutlein
Single-cell analyses of axolotl telencephalon organization, neurogenesis, and regeneration
Science, 377, DOI: 10.1126/science.abp9262 . (2022).external pagearticlecall_made

Z. He, A. Maynard, A. Jain, T. Berber, R. Petri, H. Lin, M. Santel, K. Ly, J. Dupré, L. Sidow, F. Sanchis Callejal, S. Jansen, S. Riesenberg, J. G. Camp and B. Treutlein
Lineage recording in human cerebral organoids
Nat Methods, 19, pages 90–99 . (2022).external pagearticlecall_made

S. P. Pașca, P. Arlotta, H. S. Bateup, J. G. Camp, S. Cappello, F. H. Gage, J. A. Knoblich, A. R. Kriegstein, M. A. Lancaster, G. Ming, A. R. Muorti, I. Park, O. Reiner, H. Song, L. Studer, S. Temple, G. Testa, B. Treutlein and F. M. Vaccarino
A nomenclature consensus for nervous system organoids and assembloids
Nature, 609, pages 907–910 . (2022).external pagearticlecall_made

N. Oskolokov, M. Santel, H. M. Parikh, O. Ekström, G. J. Camp, E. Miyamoto-Mikami, K. Stöm, B.A. Mir, D. Kryvokhyzha, M. Lehtovirta, H. Kobayashi, R. Kakigi, H. Naito, K. Eriksson, B. Nystedt, N. Fuku, B. Treutlein, S. Pääbo and O. Hansson
High-throughput muscle fiber typing from RNA sequencing data
Skeletal Muscle, 12, Article number: 16 . (2022).external pagearticlecall_made

D. Wollny, B. Vernot, J. Wang, M. Hondele, A. Safrastyan, F. Aron, J. Micheel, Z. He, A. Hyman, K. Weis, J. G. Camp, T-Y D. Tang and B. Treutlein
Characterization of RNA content in individual phase-separated coacervate microdroplets
Nat Commun, May 12;13(1):2626. doi: 10.1038/s41467-022-30158-1. (2022).external pagearticlecall_made

J. Krumm, K. Sekine, P. Samaras, A. Brazovskaja, M. Breunig, Y. Yasui, A/ Kleger, H. Taniguchi, M. Wilhelm, B. Treutlein, J. G. Camp and B. Kuster
High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development
Cell Rep., Mar 29;38(13):110604. doi: 10.1016/j.celrep.2022.110604. (2022).external pagearticlecall_made

T. Gerber, C. Loureiro, N. Schramma, S. Chen, A. Jain, A. Weber, A. Weigert, M. Santel, K. Alim, B. Treutlein and J. G. Camp
Spatial transcriptomic and single-nucleus analysis reveals heterogeneity in a gigantic single-celled syncytium
elife, Feb 23;11:e69745. doi: 10.7554/eLife.69745. (2022).external pagearticlecall_made

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C. Kyrousi, A. C. O’Neill, A. Brazovskaja, Z. He, P. Kielkowski, L. Coquand, R. Di Giaimo, P. D’ Andrea, A. Belka, A. F. Echeverry, D. Mei, M. Lenge, C. Cruceanu, I. Y. Buchsbaum, S.Khattak, G. Fabien, E. Binder, F. Elmslie, R. Guerrini, A. D. Baffet, S. A. Sieber, B. Treutlein, P. Robertson and S. Cappello
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity
Nat Commun, Nov 2;12(1):6298. doi: 10.1038/s41467-021-26447-w. (2021).external pagearticlecall_made

M. Haniffa, D. Taylor, S. Linnarsson, B. J. Aronow, G. D. Bader, R. A. Barker, P. G. Camara, J. G. Camp, A. Chédotal, A. Copp, H. C. Etchevers, P. Giacobini, B. Göttgens, G. Guo, A. Hupalowska, K. R. James, E. Kirby, A. Kriegstein, J. Lundeberg, J. C. Marioni, K. B. Meyer, K. K. Niakan, M. Nilsson, B. Olabi, D. Pe’er, A. Regev, J. Rood, O. Rozenblatt-Rosen, R. Satija, S. A. Teichmann, B. Treutlein, R. Vento-Tormo, S. Webb & Human Cell Atlas Developmental Biological Network-Show fewer authors
A roadmap for the Human Developmental Cell Atlas
Nature, Sep;597(7875):196-205(2021).external pagearticlecall_made
 

G. Born, M. Nikolova, A. Scherberich, B. Treutlein, A. García-García and I. Martin
Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells
J. Tissue Eng, Sep 29;12:20417314211044855. doi: 10.1177/20417314211044855(2021).external pagearticlecall_made

H. Lin, Z. He. S. Ebert, M. Schörnig, M. Santel, M. T. Nikolova, A. Weigert, W. Hevers, N. N. Kasri, E. Taverna, J. G. Camp and B. Treutlein
NGN2 induces diverse neuron types from human pluripotency
Stem Cell Reports, Jul 22;S2213-6711(21)00372-6 (2021).external pagearticlecall_made

Q. Yu, U. Kilik, E. M. Holloway. Y. Tsai, C. Harmel, A. Wu, J. H. Wu, M. Czerwinski, C. J. Childs, Z. He, M. M. Capeling, S. Huang, I. A. Glass, P. D. R. Higgins, B. Treutlein, J. R. Spence and J. G. Camp
Charting human development using a multi-endodermal organ atlas and organoid models
Cell, https://doi.org/10.1016/j.cell.2021.04.028(2021).external pagearticlecall_made

T. Lin, T. Gerber, Y. Taniguchi-Sugiura, P. Murawala, S. Hermann, L. Grosse, E. Shibata, B. Treutlein and E. M. Tanaka
Fibroblast dedifferentiation as a determinant of successful regeneration
Dev Cell, 56(10):1541-1551.e6(2021).external pagearticlecall_made

J. S. Fleck, F. Sanchis-Calleja, Z. He, M. J. Boyle, J. G. Camp and B. Treutlein
Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases
Cell Stem Cell, DOI:https://doi.org/10.1016/j.stem.2021.02.015(2021).external pagearticlecall_made

E. M. Holloway, M. Czerwinski, Y. Tsai, J. H. Wu, A. Wu, C. J. Childs, K. D. Walton, C. W. Sweet, Q. Yu, I. Glass, B. Treutlein, J. G. Camp and J. R. Spence
Mapping Development of the Human Intestinal Niche at Single-Cell Resolution
Cell Stem Cell, 28(3):568-580.e4. (2021).external pagearticlecall_made

M. Schornig, X. Ju, L. Fast, S. Ebert, A. Weigert, S. Kanton, T. Schaffer, N. Nadif Kasri, B. Treutlein, B. M. Peter, W. Hevers and E. Taverna
Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes
eLife, 10, e59323 (2021).external pagearticlecall_made


C. Bock, M. Boutros, J. G. Camp, L. Clarke, H. Clevers, J. Knoblich, P. Liberali, A. Regev, A. C. Rios, O. Stegle, H. G. Stunnenberg, S. A. Teichmann, B. Treutlein, R. G. J. Vries and the Human Cell Atlas 'Biological Network' Organoids
The Organoid Cell Atlas
Nature Biotechnology, 39, 13-17 (2021).external pagearticlecall_made

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G. Brancati, B. Treutlein and J. G. Camp
Resolving Neurodevelopmental and Vision Disorders Using Organoid Single-Cell Multi-omics
Neuron, 107, 1000-1013 (2020). external pagearticlecall_made

M. Dannemann, Z. He, C. Heide, B. Vernot, L. Sidow, S. Kanton, A. Weigert, B. Treutlein, S. Paabo, J. Kelso and J. G. Camp
Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions
Stem Cell Reports, 15, 214-225 (2020). external pagearticlcall_made

B. Treutlein and J. G. Camp
Sequencing perturbed cortex development
Science, 370(6520):1038-1039 doi: 10.1126/science.abf3661(2020). external pagearticlecall_made

Z. He, A. Brazovskaja, S. Ebert, J. G. Camp and B. Treutlein
CSS: cluster similarity spectrum integration of single-cell genomics data
Genome Biology, 21, Article number: 224 (2020). external pagearticlecall_made

S. Kanton, B. Treutlein and J. G. Camp
Single-cell genomic analysis of human cerebral organoids
Methods Cell Biol, 159, 229-256 (2020). external pagearticlecall_made

E. Khrameeva, I. Kurochkin, D. Han, P. Guijarro, S. Kanton, M. Santel, Z. Qian, S. Rong, P. Mazin, M. Sabirov, M. Bulat, O. Efimova, A. Tkachev, S. Guo, C. C. Sherwood, J. G. Camp, S. Paabo, B. Treutlein and P. Khaitovich
Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains
Genome research, 30, 776-789 (2020). external pagearticlecall_made

A. L. McGuire, S. Gabriel, S. A. Tishkoff, A. Wonkam, A. Chakravarti, E. E. M. Furlong, B. Treutlein, A. Meissner, H. Y. Chang, N. Lopez-Bigas, E. Segal and J. S. Kim
The road ahead in genetics and genomics
Nat Rev Genet, 21, 581-596 (2020). external pagearticlecall_made

A. J. Miller, Q. Yu, M. Czerwinski, Y-H. Tsai, R. F. Conway, A. Wu, E. M. Holloway, T. Walker, I. A. Glass, B. Treutlein, J. G. Camp and J. R. Spence
In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution
Developmental Cell, DOI:https://doi.org/10.1016/j.devcel.2020.01.033 (2020). external pagearticlecall_made

K. Sekine, S. Tsuzuki, R. Yasui, T. Kobayashi, K. Ikeda, Y. Hamada, E. Kanai, J. G. Camp, B. Treutlein, Y. Ueno, S. Okamoto and H. Taniguchi
Robust detection of undifferentiated iPSC among differentiated cells
Scientific reports, 10, 10293 (2020). external pagearticlecall_made

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S. Kanton, M. Boyle, Z. He, M. Santel, A. Weigert, F. Sanchis Calleja, L. Sidow, J. Fleck, P. Guijarro, D. Han, Z. Qian, M. Heide, W. B. Huttner, P. Khaitovich, S. Pääbo, B. Treutlein and J.G. Camp
Single-cell genomic atlas of great ape cerebral organoids uncovers human-specific features of brain development
Nature, 574 418-422 (2019). external pagearticlecall_made

J.G.Camp, R.Platt and B. Treutlein
Mapping human cell phenotypes to genotypes with single-cell genomics
Science 365,1401-1405 (2019). external pagereviewcall_made

R.G Parra, N. Papadopoulos, L. Ahumada-Arranz, J.E. Kholtei, N. Mottelson, Y. Horokhovsky, B. Treutlein and J. Soeding.
Reconstructing complex lineage trees from scRNA-seq data using MERLoT
Nucleic Acids Res., 47(17), 8961-8974. doi: 10.1093/nar/gkz706. (2019). external pagearticlecall_made

A.M. Klein and B. Treutlein
Single cell analyses of development in the modern era
Development, 146(12), pii: dev181396. doi: 10.1242/dev.181396. (2019). external pagearticlecall_made

W. Koh, A. Wu, L. Penland, B. Treutlein, N. F. Neff, G. L. Mantalas, Y. J. Blumenfeld, Y. Y. El-Sayed, D. K. Stevenson, G. M. Shaw, and S. R. Quake
Single Cell Transcriptomes Derived from Human Cervical and Uterine Tissue during Pregnancy
Adv Biosyst, 3, e1800336 (2019). external pagearticlecall_made

J. Klaus, S. Kanton, C. Kyrousi, A.C. Ayo-Martin, R. Di Giaimo, S. Riesenberg, A.C. O’Neill, J.G. Camp, C. Tocco, M. Santel, E. Rusha, M. Drukker, M. Schroeder, M. Götz, S.P. Robertson, B. Treutlein and S. Cappello
Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia
Nature Medicine, 25, 561-568 (2019). external pagearticlecall_made

J.G.Camp and B. Treutlein
Evaluation of Wu et al.: Strengthening Single-Cell Bioinformatic Comparisons for Improving Organoid Differentiation
Cell stem Cell, 24(3),343-344 (2019). external pagearticlecall_made

A. Brazovskaja, B. Treutlein and G. Camp.
High-throughput single-cell transcriptomics on organoids
Currrent Opinion in Biotechnology, 55, 167-171 (2019). external pagearticlecall_made

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T. Gerber*, P. Murawala*, D. Knapp*, W. Masselink, M. Schuerz, S. Hermann, M. Gac-Santel, S. Nowoshilow, J. Kagejama, S. Khattak, J. Currie, J.G. Camp, E.M. Tanaka* and B. Treutlein*.
Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration.
Science 362 (2018). external pagearticlecall_made

J.G. Camp, D. Wollny, and B. Treutlein.
Single-cell genomics to guide human stem cell and tissue engineering.
Nature Methods, 15, 661-667 (2018). external pagearticlecall_made

M. Karow*, J.G. Camp*, S. Falk, T. Gerber, A. Pataskar, M. Gac-Santel, J. Kageyama, A. Brazovskaja, A. Garding, W. Fan, T. Riedemann, A. Casamassa, A. Smiyakin, C. Schichor, M. Götz, V.K. Tiwari, B. Treutlein* and B. Berninger*.
Pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program.
Nature Neuroscience, 21, 932-940 (2018). external pagearticlecall_made

H. Ayabe, T. Anada, T. Kamoya, T. Sato, M. Kimura, E. Yoshizawa, S. Kikuchi, Y. Ueno, K. Sekine, J. G. Camp, B. Treutlein, A. Ferguson, O. Suzuki, T. Takebe and H. Taniguchi.
Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling.
Stem Cell Reports, 11(2), 306-316 (2018). external pagecall_madeexternal pagearticlecall_made

J.M. Churko, P. Garg, B. Treutlein, M. Venkatasubramanian, H. Wu, J. Lee, Q. N. Wessells, S. Y. Chen, W. Y. Chen, K. Chetal, G. Mantalas, N. Neff, E. Jabart, A. Sharma, G. P. Nolan, N. Salomonis and J. C. Wu.
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis.
Nat Commun, 9(1), 4906 (2018). external pagearticlecall_made

S. Vaid, J. G. Camp, L. Hersemann, C. Eugster Oegema, A. K. Heninger, S. Winkler, H. Brandl, M. Sarov, B. Treutlein, W. B. Huttner and T. Namba.
A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex.
Development, 145(20) (2018). external pagearticlecall_made

J. Kageyama, D. Wollny, B. Treutlein* and J. G. Camp*.
ShinyCortex: Exploring Single-Cell Transcriptome Data From the Developing Human Cortex.
Front Neurosci, 12, 315 (2018). external pagearticlecall_made

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