New D-BSSE startup revolutionises treatment of metabolic diseases

CreARTO Bioscience, a recently founded ETH startup originating from the Biotechnology lab of Martin Fussenegger, offers a synthetic biology-based platform technology that reprograms stem cells for the treatment of metabolic diseases. The first product will target type 1 diabetes.

After years of research in the Fussenegger lab, the startup CreARTO Bioscience AG was founded with six co-founders from different fields of expertise. The team consists of experienced and leading biologists, physicians and economists. Two co-founders from D-BSSE are Prof. Martin Fussenegger and Dr. Ana Palma Texeira (CSO).

Millions of people suffer from type 1 diabetes. (Colourbox)
Millions of people suffer from type 1 diabetes. (Image: Colourbox)

The new D-BSSE startup will fundamentally change the treatment paradigm for insulin-dependent patients with a synthetic biology-based platform technology. With the unique genetic software it is possible to reprogram stem cells. This will allow CreARTO to treat metabolic diseases in a groundbreaking way using modified cells. This disruptive technology creates the opportunity to change the life of millions of patients with type 1 diabetes.

The first lead indication is type 1 diabetes. The therapeutic agent consists of islet cells differentiated in vitro from human stem cells, which constitute an unlimited cell source for transplantation into patients who lost their insulin-producing beta cells. The therapeutic cells will be encapsulated in immunoprotected capsules to alleviate safety concerns while enabling control of glucose homeostasis.

CreARTO research & development

Find information on the Biotechnology lab led by Martin Fussenegger.

Learn about all D-BSSE spinoff companies.

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