Biotechnology applications
Multidimensional drug screening assays
Drug discovery is a labor intensive process, because an ideal drug should be effective against its intended molecular target and at the same time not interact with unintended cellular components. These tests are usually done sequentially. Using information-processing networks, it is possible to assess desired (on-target) and undesired (off-target) effects simultaneously. We develop these new assays for different classes of drug targets. Recently, we published a work on an assay for microRNA drug discovery. A work in progress focuses on GPCR targets.
Further reading
Synthetic biology for biomanufacturing
Biomanufacturing of protein therapeutics using mammalian cell lines is a well-established technology, yet its roots date back to the early days of molecular biology and genetic engineering. We are working to place the process of firm engineering foundation by rethinking the entire process of developing cells used for biomanufacturing.