Publications
The indexed publications can also be accessed via the external pageGoogle Scholar ID of Sven Panke, just click on the icon below.
Selected publications
external pageEfficient synthesis of 2,6.bis(hydroxymethyl)pyridine using whole-cell biocatalysis. Kardashliev, T., Panke, S., & M. Held. Green Chem. (2022).
external pageOptimization of the antimicrobial peptide Bac7 by deep mutational scanning. Koch, P., Schmitt, S., Heynisch, A., Gumpinger, A., Wüthrich, I., Gysin, M., Shcherbakov, D., Hobbie, S. N., Panke, S., & M. Held. BMC Biol. (2022).
external pageA multiplexed cell-free assay to screen for antimicrobial peptides in double emulsion droplets. Nuti, N.1, Rottmann, P.1, Stucki, A., Koch, P., Panke, S., & P. S. Dittrich. Angew. Chem. Int. (2022).
external pageDirected evolution of biofuel-responsive biosensors for automated optimization of branched-chain alcohol biosynthesis. Bahls, M., Platz, L., Morgado, G., Schmidt, G. W., & S. Panke. Metabol. Eng. (2022).
external pageWhole-cell screening of oxidative enzymes using genetically encoded sensors. Kardashliev, T., Weingartner, A., Romero, E., Schwaneberg, U., Fraaije, M., Panke, S., and M. Held. Chem. Sc. (2021).
external pageAcoustofluidic medium exchange for preparation of electrocompetent bacteria using channel wall trapping. Gerlt, M. S., Ruppen, P., Leuthner, M., Panke, S., and J. Dual. Lab Chip (2021).
external pagePlasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H K Becker, A Meyer, TM Roberts, S Panke. Nucleic Acids Research (2021).
external pageSystematic engineering of artificial metalloenzymes for new-to-nature reactions. T Vornholt , F Christoffel, MM Pellizzoni, S Panke, TR Ward, M Jeschek. Science Advances (2021).
external pageHigh-Throughput Optimization of Recombinant Protein Production in Microfluidic Gel Beads M Napiorkowska, L Pestalozzi, S Panke, M Held, S Schmitt. Small (2021).
external pageLarge-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping. S. Höllerer, L. Papaxanthos, A.C. Gumpinger, K. Fischer, C. Beisel, K. Borgwardt, Y. Benenson & M. Jeschek. Nature Communications (2020).
external pageUltra-high throughput screening for novel protease specificities. E. Rousounelou, S. Schmitt, L. Pestalozzi, M. Held, T.M. Roberts & S. Panke. Methods in Enzymology (2020).
external pageThe Quest for Xenobiotic Enzymes: From New Enzymes for Chemistry to a Novel Chemistry of Life. T. Vornholt & M. Jeschek. ChemBioChem (2020).
external pageSemi-rational engineering of an amino acid racemase that is stabilized in aqueous/organic solvent mixtures. C. Femmer, M. Bechtold & S. Panke. Biotechnology and Bioengineering (2020).
external pageIn vivo directed enzyme evolution in nanoliter reactors with antimetabolite selection. C. Femmer, M. Bechtold, M. Held & S. Panke. Metabolic Engineering (2020).
external pageTaming the Beast of Biology: Synthetic Biology and Biological Systems Engineering. S. Panke. CHIMIA International Journal for Chemistry (2020).
external pageDevelopment and optimisation of a defined high cell density yeast medium. T.M. Roberts, H.-M. Kaltenbach & F. Rudolf. Yeast (2020).
external pageEditorial overview: Beyond canonical biochemistry. S. Panke & T. Ward. Current Opinion in Biotechnology (2019).
external pageAnalysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale. S. Schmitt, M. Montalbán-López, D. Peterhoff, J. Deng, R. Wagner, M. Held, O.P. Kuipers & S. Panke. Nature Chemical Biology (2019).
external pageMutant variants of the substrate-binding protein DppA from Escherichia coli enhance growth on nonstandard γ-glutamyl amide-containing peptides. T. Kuenzl, X. Li-Blatter, P. Srivastava, P. Herdewijn, T. Sharpe & S. Panke. Applied and Environmental Microbiology (2018).
external pageIdentification and Characterisation of a pH-stable GFP. T.M. Roberts, F. Rudolf, A. Meyer, R. Pellaux, E. Whitehead, S. Panke & M. Held. Scientific Reports (2018).
external pageArchimedes’ principle for characterisation of recombinant whole cell biocatalysts. S. Schmitt, M. Walser, M. Rehmann, S. Oesterle, S. Panke & M. Held. Scientific Reports (2018).
external pageSequence-based prediction of permissive stretches for internal protein tagging and knockdown. S. Oesterle, T. M. Roberts, L. A. Widmer, H. Mustafa, S. Panke & S. Billerbeck. BMC Biology (2017).
external pageOvercoming the membrane barrier: Recruitment of γ-glutamyl transferase for intracellular release of metabolic cargo from peptide vectors. T. Kuenzl, M. Sroka, P. Srivastava, P. Herdewijn, P. Marlière & S. Panke. Metabolic Engineering (2017).
external pageForward design of a complex enzyme cascade reaction. C. Hold, S. Billerbeck & S. Panke. Nature Communications (2016).
external pageDirected evolution of artificial metalloenzymes forin vivometathesis. M. Jeschek, R. Reuter, T. Heinisch, C. Trindler, J. Klehr, S. Panke & T.R. Ward. Nature (2016).
external pageRationally reduced libraries for combinatorial pathway optimization minimizing experimental effort. M. Jeschek, D. Gerngross & S. Panke. Nature Communications (2016).
external pageOptimization of a whole-cell biocatalyst by employing genetically encoded product sensors inside nanolitre reactors. A. Meyer, R. Pellaux, S. Potot, K. Becker, H.-P. Hohmann, S. Panke & M. Held. Nature Chemistry (2015).
external pageA Separation-Integrated Cascade Reaction to Overcome Thermodynamic Limitations in Rare-Sugar Synthesis. N. Wagner, A. Bosshart, J. Failmezger, M. Bechtold & S. Panke. Angewandte Chemie - International Edition (2015).
external pageSystematic optimization of interface interactions increases the thermostability of a multimeric enzyme. A. Bosshart, S. Panke & M. Bechtold. Angewandte Chemie - International Edition (2013).
external pageThe good of two worlds. Increasing complexity in cell-free systems. S. Billerbeck, J. Härle & S. Panke. Current Opinion in Biotechnology (2013).
external pageOptimization of a blueprint for in vitro glycolysis by metabolic real-time analysis. M. Bujara, M. Schümperli, R. Pellaux, M. Heinemann & S. Panke. Nature Chemical Biology (2011).