09

Congrats to Tania. Her newest paper, appearing in Nature Chemical Biology, describes how the chaperone/translocase YidC supports the insertion and folding of the sugar transporter lactose permease LacY. YidC prevents the LacY polypeptide from misfolding and supports the stochastic and stepwise insertion and folding of structural segments until the folding of native LacY has been completed. The work was done together with Ron Kaback UCLA.