PhD Theses

2023

Lee, Jihyun
Development of a high-density microelectrode-array-based platform for studying cardiac arrhythmias and drug responses
ETH Zurich, No. 29734
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Alessio Buccino, ETH Zurich, Dr. Hasan Ulusan, ETH Zurich & Prof. Dr. Firat Duru, University of Zurich)

Kim, Taehoon
Connectivity inference and graphical analysis of spike-sorted neurons using high-density microelectrode arrays
ETH Zurich, No. 28384
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Manuel Schröter, ETH Zurich & Prof. Dr. Karsten Borgwardt, Max-Planck Institute Martinsried, Germany)

Wei, Wei
Scalable in vitro blood-brain-barrier models for biological and pharmaceutical research
ETH Zurich, No. 29381
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Mario Modena, ETH Zurich & Prof. Dr. Carlotta Guiducci, EPF Lausanne)

Xue, Xiaohan
Multimodal approaches to investigate neuronal activity using optical imaging techniques and high-density microelectrode arrays
ETH Zurich, No. 29380
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Alessio Buccino, ETH Zurich, Dr. Julian Bartram, ETH Zurich & Prof. Dr. Ulrich Egert, University of Freiburg, Germany)

2022

Gökce, Furkan
Translational engineering for addressing limitations in leukemia drug screening
ETH Zurich, No. 28952
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Mario Modena, ETH Zurich, Prof. Dr. Timm Schroeder, ETH Zurich & Prof. Dr. Philippe Renaud, EPF Lausanne)

Nguyen, Thi Phuong Oanh
Integrating immune components into microphysiological systems for disease modeling and therapy testing
ETH Zurich, No. 28899
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Patrick Misun, Novartis AG, Basel, Dr. Christian Lohasz, ETH Zurich & Prof. Dr. Sai Reddy, ETH Zurich)

Znidaric, Matej
Studying signaling of retinal ganglion and amacrine cells by means of high-density microelectrode arrays
ETH Zurich No. 28845
(Prof. Dr. A. Hierlemann, ETH Zurich, Prof. Dr. Felix Franke, IOB, University of Basel & Prof. Dr. Botond Roska, IOB, University of Basel)

Bucci, Annalisa
Spatial aspects of retinal processing in the outer retina and human retinal nerve fiber layer
ETH Zurich No. 28798
(Prof. Dr. A. Hierlemann, ETH Zurich, Prof. Dr. Felix Franke, IOB, University of Basel & Prof. Dr. Botond Roska, IOB, University of Basel)

Bounik, Raziyeh
Integration of CMOS sensors and circuits into microphysiological hanging- and standing-drop net-works
ETH Zurich No. 28772
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Mario Modena, ETH Zurich, Dr. Vijay Viswam, MaxWell Biosystems AG, Zurich & Prof. Dr. Carlotta Guiducci, EPF Lausanne)

Rousset, Nassim
Developing modeling approaches for microfluidic drop networks
ETH Zurich, external pageNo. 28280call_made
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Patrick Misun, Novartis AG, Basel & Prof. Dr. Dagmar Iber, ETH Zurich)

2021

Ravaynia, Paolo
Miniaturized impedance-based platforms for parallelized and real-time assessment of an-tischistosomal drug potency
ETH Zurich, No. 27756
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Mario Modena, ETH Zurich & Prof. Dr. Carlotta Guiducci, EPF Lausanne)

Boos, Julia
Microfluidic co-culture platforms for advanced embryotoxicity testing in vitro
ETH Zurich, No. 27476
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Tina Bürki-Thurnherr, EMPA, St. Gallen & Prof. Dr. Barbara Treutlein, ETH Zurich)

Ronchi, Silvia
Electrical stimulation and functional characterization of neurons using high-density microelectrode arrays
ETH Zurich, No. 27495
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Michele Fiscella, MaxWell Biosystems AG, Zurich & Prof. Dr. Ulrich Egert, Albert-Ludwigs University of Freiburg, Germany)

2020

Yuan, Xinyue
Dual-mode CMOS-based microelectrode array for extracellular action potential recordings to study neural networks
ETH Zurich, No. 26824
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Urs Frey, MaxWell Biosystems AG, Zurich, Prof. Dr. Giacomo Indiveri, ETH Zurich & Prof. Dr. Kenneth Kosik, UC Santa Barbara)

Lohasz, Christian
Gravity-driven perfusion systems for the physiological culturing of arrays of microtissues
ETH Zurich, No. 26595
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Olivier Frey, InSphero AG, Schlieren & Prof. Dr. Petra Dittrich, ETH Zurich)

2019

Nudischer, Ramona
Characterization and application of a mouse three-dimensional liver system in drug development
ETH Zurich, No. 26500
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Adrian Roth, Hoffmann-La Roche Inc., Basel & Prof. Dr. Petra Dittrich, ETH Zurich)

Diggelmann, Roland
High-throughput detection and functional classification of retinal ganglion cells using high-density microelectrode arrays
ETH Zurich, No. 26478
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Felix Franke, ETH Zurich, & Prof. Dr. Botond Roska, IOB, University of Basel)

2018

Chawla, Ketki
Microfluidic platforms with integrated impedance measurements for cells and parasitic worms
ETH Zurich, No. 25612
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Olivier Frey, InSphero AG, Schlieren & Prof. Dr. Carlotta Guiducci, EPF Lausanne)

Dudina, Alexandra
Large-scale CNTFET sensor arrays in CMOS technology
ETH Zurich, No. 25630
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Urs Frey, MaxWell Biosystems AG, Basel & Prof. Dr. Christofer Hierold, ETH Zurich)

Kaestli, Alicia
Microfluidic strategies for studying communication between cells and tissues 
ETH Zurich, No. 25495
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Olivier Frey, InSphero AG, Schlieren & Prof. Dr. Timm Schroeder, ETH Zurich)

Misun, Patrick
Microfluidic hanging-drop platforms for 3D microtissue culture and analysis
ETH Zurich, No. 25393
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Olivier Frey, InSphero AG, Schlieren & Prof. Dr. Petra Dittrich, ETH Zurich)

van Lier, Ben
Analysis of local field potentials in organotypic hippocampal cultures of NMDA receptor subunit knockout mice
ETH Zurich, No. 25392
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Frederic Knoflach, Hoffmann-La Roche Inc., Basel & Prof. Benjamin Hall, Tulane University)

Gong, Wei
Brain slice recordings on high-density microelectrode arrays, from single-unit activity tracking to network investigations
ETH Zurich, No. 25286
(Prof. Dr. A. Hierlemann, ETH Zurich, Dr. Frederic Knoflach, Hoffmann-La Roche Inc., Basel & Prof. Beat Gähwiler, University of Zurich)

Schmidt, Gregor
Microfluidics for long-term culture and imaging of yeast at single cell resolution
ETH Zurich, No. 25086
(Prof. Dr. A. Hierlemann, ETH Zurich, Prof. Dr. Petra Dittrich, ETH Zurich & Prof. Dr. Mark Leake, University of York)

2016

Radivojevic, Milos
From selective stimulation to single-spike detection: Interfacing neocortical neurons with thousands of microelectrodes at subcellular spatial resolution
ETH Zurich, No. 24073
(Prof. Dr. Andreas Hierlemann, Dr. Douglas Bakkum, ETH Zurich & Prof. Dr. Fritjof Helmchen, University of Zurich)

Shadmani, Amir
CMOS integrated circuits for microelectrode arrays and design of experimental setups
ETH Zurich, No. 24004
(Prof. Dr. A. Hierlemann, ETH Zurich, Prof. Dr. Carlotta Guiducci, EPF Lausanne & Prof. Dr. Hanspeter Schmid, FH Nordwestschweiz, Windisch, Switzerland).

Viswam, Vijay
High-density multi-functional neural interface in CMOS technology
ETH Zurich, No. 24018
(Prof. Dr. A. Hierlemann, Dr. Urs Frey, ETH Zurich, Prof. Dr. Carlotta Guiducci, EPF Lausanne & Prof. Dr. Hanspeter Schmid, FH Nordwestschweiz, Windisch, Switzerland).

Dragas, Jelena
VLSI hardware devices for acquisition and processing of multielectrode neuronal signals
ETH Zurich,  No. 23913
(Prof. Dr. Andreas Hierlemann, Dr. Felix Franke & Prof. Dr. Tobi Delbrück, ETH Zurich)

Haandbaek, Niels
High-frequency impedance spectroscope for single-cell microfluidic flow cytometry
ETH Zurich, No. 23534
(Prof. Dr. A. Hierlemann, Dr. Olvier Frey & Prof. Dr. Janos Vörös, ETH Zurich).

2015

Bürgel, Sebastian
Electrical impedance spectroscopy of suspended cells and microtissue spheroids
ETH Zurich, No. 23096
(Prof. Dr. A. Hierlemann, Dr. Olivier Frey & Prof. Dr. Petra Dittrich, ETH Zurich).

Jones, Ian Lloyd
Optical and electrical stimulation of retinal ganglion cells on a CMOS microelectrode array
ETH Zurich, No. 22906
(Prof. Dr. A. Hierlemann, Dr. Karl Farrow, NERF Leuven, Belgium & Prof. Dr. Botond Roska, FMI and University of Basel).

Müller, Jan
High-density microelectrode array platform in CMOS technology
ETH Zurich, No. 22625
(Prof. Dr. A. Hierlemann, Dr. Douglas Bakkum & Prof. Dr. Tobias Delbrück, ETH Zurich).

2014

Jäckel, David
Methods for synaptic connectivity mapping, neuronal stimulation, and spike sorting using high-density microelectrode arrays and patch clamp recordings
ETH Zurich, No. 22437
(Prof. Dr. A. Hierlemann, Dr. Urs Frey, Riken, Kobe, Japan & Prof. Dr. Ulrich Egert, Albert-Ludwigs University of Freiburg, Germany).

Lewandowska, Marta
Electrochemical DNA hybridization sensor and axonal information processing device implemented on CMOS microelectrode arrays
ETH Zurich, No. 22436
(Prof. Dr. A. Hierlemann, Prof. Dr. Stephanie Lacour, EPF Lausanne, Switzerland & Prof. Dr. Ulrich Egert, Albert-Ludwigs University of Freiburg, Germany).

Rothe, Jörg
Fully integrated CMOS microelectrode array for electrochemical measurements
ETH Zurich, No. 22339
(Prof. Dr. A. Hierlemann, Dr. Olivier Frey & Prof. Dr. Roland Thewes, Technical University of Berlin, Germany).

Livi, Paolo
CMOS circuits for high-density neural interfaces and nanowire sensor arrays
ETH Zurich, No. 22085
(Prof. Dr. A. Hierlemann, Prof. Dr. Christian Schönenberger, University of Basel & Dr. Christoph Hagleitner, IBM Research, Rüschlikon, Switzerland).

Fiscella, Michele
Combining CMOS-based microelectrode arrays with genetic labeling to study visual processing in the retina
ETH Zurich, No. 22133
(Prof. Dr. A. Hierlemann, Dr. Felix Franke & Prof. Dr. Botond Roska, FMI and University of Basel).

Zhu, Zhen
Microfluidics-based single-cell manipulation, cultivation, and in situ analysis through electrical impedance spectroscopy
ETH Zurich, No. 21780
(Prof. Dr. A. Hierlemann, Prof. Dr. Daniel Müller, D-BSSE & Prof. Dr. Roland Zengerle, Albert-Ludwigs University of Freiburg, Germany).

2013

Ballini, Marco
Low-noise CMOS circuits and system design of an integrated microelectrode array with high channel count
ETH Zurich, No. 21589
(Prof. Dr. A. Hierlemann, Prof. Dr. Michiel Vellekoop, IMSAS, University of Bremen, Germany & Dr. Christoph Hagleitner, IBM Research, Rüschlikon, Switzerland).

PhD theses at the Physical Electronics Laboratory (PEL)

2007

Frey, Urs
High-density neural interface and microhotplate gas sensor in CMOS technology
ETH Zurich, No. 17460
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, Prof. Dr. K. Najafi, University of Michigan, Ann Arbor, USA & Dr. U. Egert, Albert-Ludwigs-University, Freiburg, Germany).

2006

Kurzawski, Petra
Volatile organic compound detection and enantiomer discrimination using a CMOS-based multi-sensor system
ETH Zurich, No. 16808
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, & Prof. Dr. J. Janata, Georgia Institute of Technology, Atlanta, USA).

Hafizovic, Sadik
Neural interface and atomic-force microscope in CMOS-technology
ETH Zurich, No. 16806
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, & Prof. Dr. S. Seung, MIT, Cambridge, USA & Prof. Dr. J. G. Korvink, Albert-Ludwigs-University, Freiburg, Germany).

Greve, Frauke
Micromachined platforms for manipulating and recording from cells
ETH Zurich, No.16526
(Prof. Dr. A. Hierlemann, PD. Dr. Heike Hall, Prof. Dr. H. Baltes & Prof. Dr. M. Koudelka-Hep, Universty of Neuchâtel, Switzerland).

2005

Franks, Wendy
Towards monolithic cell-based CMOS biosensors
ETH Zurich, No. 15990
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes & Prof. Dr. M. Textor)

Heer, Flavio
A CMOS-based microelectrode array for communication with eletrogenic cells
ETH Zurich, No. 16330
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, Dr. K.-U. Kirstein & Dr. R. Thewes, Infineon Technology, Munich, Germany).

Vancura, Cyril
CMOS-based resonant cantilever systems for chemical and biological sensing applications
ETH Zurich, No. 16404
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, Prof. Dr. F. Josse, Marquette University, Milwaukee, USA, & Dr. J. Lichtenberg, Uwatec AG, Hallwil, Switzerland).

Li, Yue
Signal conditioning circuitry for CMOS-based cantilever and multi-transducer microsystems
ETH Zurich, No. 16258
(Prof. Dr. A. Hierlemann, Prof. Dr. H. Baltes, Dr. K.-U. Kirstein & Prof. Dr. S. Kawahito, Shizuoka University, Japan).

2004

Kummer, Adrian
Tuning sensitivity and discrimination performance of CMOS capacitive chemical microsensor systems
ETH Zurich, No.15411
(Prof. Dr. H. Baltes, Dr. A. Hierlemann & Prof. Dr. E.T. Zellers, University of Michigan, Ann Arbor, USA).

Graf, Markus
Microhotplate-based chemical sensor systems in CMOS technology
ETH Zurich, No. 15438
(Prof. Dr. H. Baltes, Dr. A. Hierlemann & Prof. Dr. N. de Rooij, University of Neuchâtel,Switzerland).

Before 2004

2002: Hagleitner, Christoph
CMOS Single-chip gas detection system comprising capacitive, calorimetric and mass-sensitive sensors
ETH Zurich, No. 14511
(Prof. Dr. H. Baltes, Dr. A. Hierlemann & Prof. Dr. J. H. Huijsing TU Delft, The Netherlands).

1999: Koll, Andreas
MOS capacitive chemical microsystem for volatile organic compounds
ETH Zurich, No. 13460
(Prof. Dr. H. Baltes, Dr. A. Hierlemann & Prof. Dr. N. de Rooij, University of Neuchâtel, Switzerland).