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CELL SYSTEMS DYNAMICS group

▪ Molecular control of cell fates in complex cell systems
▪ Blood, pluripotent and cancer (stem/progenitor) cells
▪ Long-term imaging & single-cell dynamics quantification
▪ Quantitative molecular cell biology
Software development
µEngineering

Selected Publications

Research Papers

Loeffler, Wehling, Schneiter, Zhang, Müller-Bötticher, Hoppe, Hilsenbeck, Kokkaliaris, Endele & Schroeder
Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells
Nature 2019

Coutu*/**, Kokkaliaris*, Kunz* & Schroeder**
Multicolor quantitative confocal imaging cytometry
Nature Methods 2018

Coutu*, Kokkaliaris*, Kunz & Schroeder
Three-dimensional map of non-hematopoietic bone and bone-marrow cells and molecules
Nature Biotechnology
2017

Hoppe, Schwarzfischer, Loeffler, Kokkaliaris, Hilsenbeck, Moritz, Endele, Filipczyk, Gambardella, Ahmed, Etzrodt, Coutu, Rieger, Marr, Strasser, Schauberger, Burtscher, Ermakova, Bürger, Lickert, Nerlov, Theis & Schroeder
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios
Nature 2016

Hilsenbeck*, Schwarzfischer*, Skylaki*, Schauberger, Hoppe, Loeffler, Kokkaliaris, Hastreiter, Skylaki, Filipczyk, Strasser, Buggenthin, Feigelman, Krumsiek, van den Berg, Endele, Etzrodt, Marr, Theis** & Schroeder**
Software tools for single-cell tracking and quantification of cellular and molecular properties
Nature Biotechnology 2016

Filipczyk*, Marr*, Hastreiter*, Feigelman, Schwarzfischer, Hoppe, Loeffler, Kokkaliaris, Endele, Schauberger, Hilsenbeck, Skylaki, Hasenauer, Anastassiadis, Theis** & Schroeder**
Network plasticity of pluripotency transcription factors in embryonic stem cells
Nature Cell Biology 2015

Eilken, Nishikawa & Schroeder
Continuous single-cell imaging of blood generation from haemogenic endothelium
Nature 2009

Rieger, Hoppe, Smejkal, Eitelhuber and Schroeder
Hematopoietic cytokines can instruct lineage choice
Science 2009

Reviews

Skylaki, Hilsenbeck & Schroeder
Challenges in long-term imaging and quantification of single cell dynamics
Nature Biotechnology 2016

Hoppe, Coutu & Schroeder
Single-cell technologies sharpen up mammalian stem cell research

Nature Cell Biology 2014

Schroeder
Long-term single-cell imaging of mammalian stem cells
Nature Methods
2011

Schroeder
Hematopoietic stem cell heterogeneity: Subtypes, not unpredictable behavior
Cell Stem Cell 2010

Schroeder
Imaging stem cell driven mammalian regeneration
Nature
2008

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