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CoBi - Computational Biology Group

Higher forms of life emerge from a more sophisticated use of often conserved signalling pathways to regulate biological function. The complex behaviour of the resulting cellular signalling networks is impossible to grasp by verbal models alone. 

We develop data-driven, predictive models of biological signaling networks with a view to gain a comprehensive understanding of the dynamics and evolution of cellular signaling.

Latest Reviews


Morphogen Interpretation

Relationship between epithelial organisation and morphogen interpretation.
Iber & Vetter, 
external pageCurr Opin in Genetics & Development

Experimental Protocol

Time-lapse and cleared imaging of mouse embryonic lung explants to study 3D cell morphology and topology dynamicsGomez et al., external pageSTAR Protocols.

Bladder Cancer
(Photograph: Keystone)

ETH Globe - A new direction for cancer researchexternal page

Neural Tube Folding

ETH News - Precursor of spine and brain forms passivelyexternal page

Latest Publications


Gradient Timer

Morphogen gradients can convey position and time in growing tissues
Vetter & Iber, external pagebioRxiv, external pageTweetorial

Bladder Cancer

Morphometry and mechanical instability at the onset of epithelial bladder cancerLampart et al., external pagebioRxiv, external pageTweetorial

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