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icbn
News
Oct 15
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Isotonic regression Conjunctive Bayesian Network models
Current version
0.2-13 Aug 2010
Description
The R package icbn implements algorithms for parameter estimation and model selection for Isotonic Conjunctive Bayesian Network (I-CBN) models. I-CBNs combine isotonic regression on a partially ordered set with CBNs for estimating order constraints among events. The model has been developed to jointly estimate mutational order constraints among genetic events and a genotype-phenotype mapping (such as a fitness landscape) that is non-decreasing along the lattice of genotypes.
Download
The icbn package is distributed under the GNU General Public License.
- 0.2-13 Aug 2010: icbn_0.2-13.tar.gz, icbn_0.2-13.zip
Authors and Contributors
- Niko Beerenwinkel
- Patrick Knupfer
- Achim Tresch
Citations
- Beerenwinkel N, Knupfer P, Tresch A (2011). Learning monotonic genotype-phenotype maps. Stat Appl Genet Mol Biol, Vol. 10, Iss. 1, Art. 3.
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