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Ascona Workshop 2011
News
May 1
Our paper Reliable detection of subclonal
single-nucleotide variants in tumor cell populations appeared in Nature Communications today (see also ETH Life). In this work, we present the deepSNV algorithm and demonstrate its capability to detect subclonal mutations present in only 1/10,000 cells.
Gerstung et al. (2012) Nat Commun 3:811. DOI: 10.1038/ncomms1814.
Statistical Challenges and Biomedical Applications of Deep Sequencing Data
Scope
The rapid development of new high-throughput sequencing technologies has opened new avenues for biological investigation on an ever-growing scale, and there is great interest among statisticians in the methodological challenges inherent in this quickly evolving domain. Addressing the new statistical demands is a prerequisite for sustained progress in biological and biomedical research predicated on these new high-throughput technologies.
This interdisciplinary workshop is intended to be a forum for (i) the dissemination of cutting-edge biotechnological and methodological developments and (ii) the identification of challenging data analysis problems. The focus is on statistical, mathematical, and computational aspects addressing concrete real-world biological questions and medical applications. Specific workshop topics include algorithms for the analysis of deep sequencing data, applications to infectious diseases and cancer, integration of heterogeneous high-throughput genomic data types, and advances in statistical computing for these problems.
Date
June 5 to 10, 2011
Location
Centro Stefano Franscini, Monte Verita, Ascona, Switzerland
Confirmed keynote speakers
- Philipp Bucher, EPF Lausanne
- Michael Brudno, University of Toronto
- Chris Greenman, Welcome Trust Sanger Institute
- Willi Gruissem, ETH Zurich
- Wolfgang Huber, EMBL Heidelberg
- John Marioni, EMBL-EBI
- Sach Mukherjee, University of Warwick
- Ben Raphael, Brown University
- Mark Robinson, Walter and Eliza Hall Institute, and Garvan Institute
- Amalio Telenti, University of Lausanne
Program
Schedule (updated June 6)
Abstract book (updated May 31)
Slides of the seminars and posters are available as PDF files from the dedicate page.
Margaret Taub and Bernhard Renard were the winners of the CSF Award for, respectively, the best presentation and the best poster.
Organizing committee
Niko Beerenwinkel, Darlene Goldstein, Peter Bühlmann
Contact
Sponsoring
- Swiss National Science Foundation
- Centro Stefano Franscini
- Swiss Institute of Bioinformatics
- Contact Group for Research Matters (KGF - Kontaktgruppe für Forschungsfragen):
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