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Künzl, Tilmann

Tilmann Künzl

ETH Zürich
Tilmann Künzl
Bioverfahrenstechnik, Panke
BSA H 350
Mattenstr. 26
4058 Basel

Phone: +41 61 387 32 55
E-Mail: 

Project

As part of the Synthetic Biology group I work on the in vivo synthesis of non-canonical amino acids (ncAAs). To prevent expensive feeding of ncAAs for incorporation into proteins, the ambition of my project is to lay a solid foundation for the synthesis of these compounds in vivo from suitable precursors. My goal is to develop generalized enzymes to catalyze the final step in the biosynthesis of various ncAAs. By evolving these enzymes in a way that they have low substrate specificity towards non-canonical compounds, these enzyme can potentially serve the biosynthesis of a large number of non-canonical amino acids.

Stations

2006 – 2009 B.Sc. in Molecular Biology, University of Göttingen
2009 – 2011 M.Sc. In Microbiology and Biochemistry, University of Göttingen
2010 Research Internship at DSM Nutritional Products, Kaiseraugst/Switzerland
2011 Master's Thesis: "Characterization of the two-component system GlrK/GlrR in Escherichia coli", Department of General Microbiology, University of Göttingen
since 2011 PhD student, Department of Biosystems Science and Engineering, ETH Zurich (Prof. Dr. Sven Panke)
 

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