Femmer, Christian
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ETH Zürich
Christian Femmer
Bioprocess Laboratory D-BSSE
1058 3.50
Mattenstrasse 26
4058 Basel
Phone: +41 61 387 32 45
E-Mail:
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Project
Within the Integrated Process group I’m responsible for the characterisation and engineering of industrial useful racemases. One goal of my work is to expand the substrate range or improve the substrate acceptance of known racemases by protein engineering towards non-proteinogenic amino acids (e.g. ornithine) which can serve as building block for pharmaceuticals. Given that the direct coupling of racemisation and SMB separation requires the use of an interoperable medium the other goal of my work is to engineer racemases with good operational stability. To achieve this I’m applying a combined approach of mutagenesis to obtain and then immobilisation of optimised variants.
Education
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2002-2008
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Diploma in Biotechnology, Berlin Institut of Technology (TU Berlin)
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Work experience
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2008
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ETH Zurich, Institute of Pharmaceutical Sciences, Group Dr. Andre Gerber, diploma thesis
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2006-2008
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Berlin Institute of Technology (TU Berlin), Institute of Biotechnology
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2005-2006
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Max Planck Institute for Molecular Genetics, Berlin-Dahlem
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2004-2005
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Leibnitz Institute for Molecular Pharmacology, Berlin-Buch
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2003-2004
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Max Delbrück Center for Molecular Medicine, Berlin-Buch
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