Phone: +41 61 387 33 07
Daniel Müller has been a full Professor of Biophysics at the ETH Zurich since 1. April 2010.
Prof. Müller was born on March 22, 1965 in Bad Wimpfen, Germany and studied physics at the University of Technology of Berlin and the Hahn-Meitner-Institute in Berlin, Germany. After finishing his studies he started his Ph.D. in Biophysics at the Forschungszentrum Jülich, Germany, with Georg Büldt and at the Biozentrum Basel, Switzerland with Andreas Engel. In 1997 he finished his Ph.D. and received the Prize for the best Ph.D. thesis in Life Sciences of the University of Basel. In 2000 Daniel Müller received his habilitation ‘venia legendi’ in Biophysics from the University of Basel. In 2000 Daniel Müller continued his career as a group leader at the newly founded Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany. In 2002 Daniel Müller accepted a full professorship of Cellular Machines at the Biotechnology Center of the University of Technology, Dresden. He acted as a director of the Center from 2003-2005. In 2006 Müller co-funded one of the largest Bionanotechnology Spin-Offs in Germany. The company developing and manufacturing the world’s first robot that fully automatically conducts single-molecule experiments was sold in 2008. In 2008 Daniel Müller in a team with Carsten Werner and Ulrich Nienhaus launched a new BMBF research center for Molecular Bioengineering (B CUBE, www.bcube-dresden.de) at the TU Dresden. In December 2010 Müller accepted the Chair of Bionanotechnology at the ETH Department of Biosystems Science and Engineering (D-BSSE) in Basel. Together with Wolfgang Meier (Uni Basel) Daniel Müller in 2014 launched and co-directs the Swiss National Competence Center of Research (NCCR) Molecular Systems Engineering at Basel (www.nccr-mse.ch).
Motivation of Daniel Müller’s scientific work: Molecular interactions drive all processes in life. Because of this enormous importance it is one pertinent demand in life sciences, systems biology and synthetic biology to characterize how these interactions drive biological processes and thus to decipher fundamentals of the biological language. The research group of Daniel Müller develops bionanotechnological methods that allow quantifying inter- and intramolecular interactions of biological processes. Currently these methods allow to image cells at nanometer resolution, to quantify and localize cellular interactions at molecular resolution and to observe how individual receptors of living cells communicate. Furthermore, it became possible to quantify and structurally localize interactions that fold, stabilize and control the functional state of single membrane proteins in their native environment.
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