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Our research in general is rooted in Physics and in the Engineering disciplines and is targeted at developing microtechnological and microelectronics-based tools and methods (e.g., Complementary Metal Oxide Semiconductor, CMOS technology) to address issues and problems in Biology and Systems Biology.
(1) Integrated Bio- and Chemosensor MicrosystemsMicrotransducers, such as cantilevers or electrodes are integrated in CMOS technology with dedicated analog and digital circuitry units in complex microsensor systems. Applications include label-free DNA analysis or the detection of biomolecules. |
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(2) BioelectronicsElectroactive cells, such as heart cells and brain cells are interfaced with microelectronics. The cells are grown directly atop fully processed microelectronics chips carrying thousands of electrodes and featuring CMOS circuitry. The chips are used for, e.g., fundamental neuroscience and pharmacology. |
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(3) Microtechnology for Cell Handling and AnalysisMicrotechnological and microfluidic means are used to address and handle cells, to characterize and analyze them with applications in single-cell analysis for Systems Biology. |
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