Escobedo, Carlos, Ph.D.

Current Research

Microfluidics for single cell manipulation and analysis.

Education

Ph.D. Mechanical Engineering, 2011, University of Victoria, Canada.

Thesis: Optofluidic Nanostructures for Concentration, Transport and Sensing.

M.A.Sc. Mechanical/Biomedical Engineering, 2002, University of Toronto, Canada.

Thesis: Electroosmotic Pumping for Biomedical Applications.

B.Sc. Mechanical Engineering, 2000, Universidad Nacional Autónoma de México, México.

Thesis: Calcium Carbonate + Poly-ε-Caprolactone Biodegradable Local Drug Delivery System.

Publications

Journal articles - 133 citations to March 2012

• Escobedo, C., Gordon, R., Brolo, A. G., Sinton, D. (2012) "Optofluidic Concentration: Plasmonic Nanostructure as Concentator and Sensor", Nano Letters, 12(3), 1592-1596.
  
• Fan, M., Wang, P., Escobedo, C., Sinton, D., Brolo, A. G. (2012 accepted) "Surface-Enhanced Raman Scattering (SERS) Optrodes for Multiplexed On-Chip Sensing of Nile Blue A and Oxazine 720", Lab on a Chip.
• Escobedo, C., Vincent, S., Choudhury, A. I. K., Campbell, J., Brolo, A. G., Sinton, D., Gordon, R. (2011) “Integrated Nanohole Array Surface Plasmon Resonance Sensing Device using a Dual-Wavelength Source”, Journal of Micromechanics and Microengineering, 21, 115001, 6 pp.  [IOP Selection, achieved 500 downloads in first month after publication (top 3%)]
• Escobedo, C., Sinton, D. (2011) “Microfluidic Liquid Actuation through Ground-directed Electric Discharge”, Microfluidics and Nanofluidics, 11, 653-662.
• Scarff, B., Escobedo, C., Sinton, D. (2011) “Radial Sample Preconcentration”, Lab on a Chip, 11(6), 1102-1109.
• Escobedo, C., Brolo, A. G., Gordon, R., Sinton, D. (2010) “Flow-Through vs. Flow-Over: Analysis of Transport and Binding in Nanohole Array Plasmonic Biosensors”, Analytical Chemistry, 82(24), 10015-10020.   [Featured in Optics and Photonics News, November 2010]
  
• Sacristan, C., Escobedo, C., Bojalil, R., Izaguirre, R., Cortina, E., Aranda, A., Catrip, J., Lespron, M. C., Springall, R., Sacristan, E. (2010) “In vivo Assessment of Hemocompatibility of a Ventri-Cular Assist Device in Healthy Swine – Measurement of Inflammatory Parameters”, Archivos de Cardiologia de Mexico, 80(2), 67-76.
• Eftekhari^‡, F., Escobedo^‡, C., Ferreira, J., Duan, X., Girotto, E. M., Brolo, A. G., Gordon, R., Sinton, D. (2009) “Nanoholes as Nanochannels: Flow-Through Plasmonic Sensing”, Analytical Chemistry, 81(11), 4308-4311 (^‡Both authors contributed equally). [Featured in Nature Photonics 5, 591–597 (2011)]  [Selected for publication in Nanowerk Spotlight “Nanofluidics meets Nanoplasmonic Sensing", July 2009]
• Ren, L., Escobedo, C., Li, D. (2002) “A New Method of Evaluating the Average Electroosmotic Velocity in Microchannels”, A New Method of Evaluating the Average Electro-Osmotic Velocity in Microchannels”, Journal of Colloid and Interface Science, 254:184-189.
• Sinton, D., Escobedo-Canseco, C., Ren, L., Li, D. (2002) “Direct and Indirect Electroosmotic Flow Velocity Measurement in Microchannels”, Journal of Colloid and Interface Science, 254, 238-242.
• Ren, L., Escobedo, C., Li, D. (2001) “Electroosmotic Flow in a Mirocapillary with One Solution Displacing Another Solution”, Journal of Colloid and Interface Science, 242, 264-271.

Selected Proceedings Contributions

• Escobedo, C., Brolo, A., Gordon, R., Sinton, D. (2011) “Nanoplasmonics as nanofluidics: transport and sensing in flowthrough nanohole arrays”, Proceeding of SPIE Photonics West, San Francisco, CA, vol. 7929, pp 7929Q-10.   [Featured in SPIE Newsroom, February 2011]

• Escobedo, C., Sinton, D. (2010) “Directed Corona Discharge for Microfluidic Liquid Actuation and Control,” Proceedings of IMECE2010, 2010 ASME International Mechanical Engineering Congress and Exposition, Vancouver, BC.
• Escobedo, C., Scarff, B., Brolo, A. G., Gordon, R., Sinton, D. (2010) “Electrokinetic Concentration and Sensing In Plasmonic Nanohole Arrays,” Proceedings of IMECE2010, 2010 ASME International Mechanical Engineering Congress and Exposition, Vancouver, BC.
• Escobedo, C., Brolo, A. G., Gordon, R., Sinton, D. (2010) “Nanofluidics meets Plasmonics: Flow-Through Surface-Based Sensing”, Proceedings of the 8th international Conference on Nanochannels, Microchannels and Minichannels and 3rd joint US-European Fluids Engineering Summer Meeting, Montreal, QC.
• Escobedo, C. and Sinton, D. (2010) “Microfluidic Liquid Actuation with Corona Discharge,” Proceedings of the Canadian Society for Mechanical Engineering Forum, Victoria, BC.
• Campbell, J., Escobedo, C., Choudhury, A. I. K., Blakely, J. T., Brolo, A. G., Sinton, D., Gordon, R. (2010) “Handheld Nanohole Array Surface Plasmon Resonance Sensing Platform.” Photonics North 2010, 7750, 77502G, Niagara Falls, ON.

Selected Conference Presentations

• Escobedo, C., Brolo, A. G., Gordon, R., Sinton, D. “Optofluidic Sieving with Flow-Through Plasmonic Nanohole Arrays,” Conference on Lasers and Electro-Optics (CLEO) and Quantum Electronics and Laser Science Conference (QELS), San Jose, CA, May 2010.   [Featured in Optics and Photonics News, November 2010]
• Escobedo, C., Wood, P., Gordon, R., Brolo, A. G., Sinton, D. “Flow-Through Nanohole Array Based Sensing,” ASME International Mechanical Engineering Conference and Exposition, Lake Buena Vista, FL, November 2009.
• Scarff, B., Escobedo, C., Sinton, D. "Radial Pre-Concentration with a Planar Nano-Porous Film,” ASME International Mechanical Engineering Conference and Exposition, Lake Buena Vista, FL, November 2009.
• Sinton, D., Escobedo, C., Wood, P., Eftekhari, F., Ferreira, J., Brolo, A. G., Gordon, R. “Microfluidic and nanofluidic integration of plasmonic substrates for biosensing,” Proceedings of SPIE, Microphotonic Devices for Biosensing I, Orlando, FL, April 2009.
• Eftekhari , F., Ferreira, J., Santos, M. J., Escobedo, C., Brolo, A. G., Sinton, D., Gordon, R. “Development of portable SPR sensor devices based on integrated periodic arrays of nanoholes,” Proceeding of SPIE, SPR Sensors, Prague, Czech Republic, April 2009.
• Brolo, A. G., Ferreira, J., Santos, M. J., Escobedo, C., Sinton, D., Girotto, E. M., Eftekhari, F., Gordon, R “Development of plasmonic substrates for biosensing,” Proceedings of SPIE, Advances in Surface Plasmon Resonance, Biosensing, San Diego, CA, August 2008.
• Escobedo, C., Ferreira, J., Eftekhari, F., Gordon, R., Brolo, A. G., Sinton, D. “Solid and fluid mechanics of flow-through nanohole array based sensing,” PCAMM Annual Meeting, Victoria, B.C., Canada, November 2008.
• Escobedo, C., Ferreira, J., Eftekhari, F., Gordon, R., Brolo, A. G., Sinton, D. “Nanofluidic transport in flow-through nanoaperture based sensing,” The 20th International Symposium on Transport Phenomena ISTP-20, Victoria, BC, July 2009.
• Escobedo, C., Eftekhari, F., Ferreira, J., Wood, P., Gordon, R., Brolo, A. G., Sinton, D. “Nanohole arrays as optical and fluidic elements for sensing,” ASME International Mechanical Engineering Congress and Exposition, Boston, MA, October 2008.
• Eftekhari, F., Escobedo, C., Ferreira, J., Wood, P., Gordon, R., Brolo, A. G., Sinton, D. “Biaxial nanohole array sensing and optofluidic integration,” IEEE/LEOS Summer Topicals 2008, Acapulco, Mexico, July 2008.
• Escobedo, C., Tovar, F., Vilá, A., Garcia, J., Suárez, B., Corona, F., Sacristan, E. “Hydrodynamic effects of the partial opening of a trileaflet valve,” 28th Annual International Conference of the IEEE/EMBS, New York, NY, August 2006.

Industrial Experience

Manager of the Mechanical Engineering Division, Innovamedica R&D: Sept. 2005 – Jul. 2007 · Founded and managed the mechanical engineering division.

R&D Engineer, Innovamedica R&D: Jun. 2003 – Aug. 2005 · Developed medical equipment, including components of a Ventricular Assist Device (VAD).

Teaching Experience

Lecturer, Department of Mechanical Engineering, University of Victoria: May–Aug. 2010. Course: Instrumentation (Instructed full course, coordinated 3 TAs and 1 lab technician, 4^th year course)

Teaching Assistant, Department of Mechanical Engineering, University of Victoria: Jan. – Apr. (2008, 2009 and 2010). Course: Fluid Mechanics (3^rd year course).

Co-Instructor, Department of Mechanical Engineering, University of Victoria: Sept. – Dec. (2008, 2009 and 2011). Course: Engineering Fundamentals I (1^st year course).

Teaching Assistant, Department of Mechanical Engineering, University of Victoria: May – Aug. (2008-2009). Course: Instrumentation (4^th year course).

Lecturer, Department of Biomedical Engineering, Monterrey Institute of Technology: Sept. – Dec. 2006. Course: Biomechanics (2^nd year course).

Lecturer, Department of Biomedical Engineering, Monterrey Institute of Technology: Jan. – May 2007. Course: Biomaterials (3^rd year course).

Lecturer, Department of Mechanical Engineering, Monterrey Institute of Tech.: Jan.–Apr., Sept.– Dec. (2003-2006). Course: Statics (1^st year course).

Lecturer, Department of Mechanical Engineering, National University of Mexico Sept. – Dec. (2003, 2006). Course: Introduction to Biomaterials (4^th year course).

Lecturer, Department of Mechanical Engineering , National University of Mexico Sept. – Dec. (2004). Course: Selected Topics in Engineering, Microtechnology (4^th year course).