Research and Thesis Projects
ETH Zurich uses SiROP to publish and search scientific projects. For more information visit external pagesirop.orgcall_made.
Controlled patterning of organoids
During development cells must assume different fates in a position-dependent manner. Morphogen gradients are able to encode this positional information, in order to guide tissue patterning during embryonic development. In the French flag model of patterning, morphogen concentration levels determine tissue domains of different cell fates. However, current in vitro 3D cell models fail to reproduce the patterning observed in vivo. Our aim is to generate 3D cell models which are able to reproduce patterning, thus allowing us to study morphogen gradients in diverse stages of development. Show details
Keywords
Organoids, organoid development, microfluidics, patterning,
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Semester Project , Master Thesis
Description
Goal
Contact Details
Published since: 2024-01-26
Earliest start: 2024-01-26
Organization: Bio Engineering Laboratory
Hosts: Modena Mario
Topics: Biology
Monitoring in-vitro neural network dynamics using microelectrode arrays
The student will culture neurons on a microelectrode array, and will record the electrical activity of the network and follow its evolution over time. The development of new methods for signal processing, neuron stimulation, and imaging can be included in the project depending on the experience and interests of the student. Show details
Keywords
Cell culture; Electrophysiology; In-vitro; Microelectrode array; Neural interface; Neural network; Neuron; Neuroscience.
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Semester Project , Course Project , Lab Practice , Bachelor Thesis , Master Thesis
Description
Contact Details
Published since: 2024-01-17
Earliest start: 2022-01-03
Organization: Bio Engineering Laboratory
Hosts: Cardes Fernando
Topics: Medical and Health Sciences , Engineering and Technology , Biology
FPGA-based platform for controlling in-vitro neuronal cultures
The student will develop an FPGA-based platform for interacting with in-vitro neuronal cultures, including real-time spike detection and neuron stimulation. The project is focused on VHDL programming, although it could include other software development and/or wet-lab tasks with neurons depending on the interests of the student. Show details
Keywords
VHDL; FPGA; Engineering; Neural interface; In-vitro neuronal culture; CMOS Microelectrode Array; Neuroscience.
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Semester Project , Internship , Bachelor Thesis , Master Thesis
Description
Contact Details
Published since: 2024-01-17
Earliest start: 2022-09-01
Organization: Bio Engineering Laboratory
Hosts: Cardes Fernando
Topics: Medical and Health Sciences , Engineering and Technology
Microelectronic circuit design for neural interfaces in 0.18um CMOS technology
This project is about the development of integrated circuits to study neurons and neural networks, and may comprise different parts of the design including analog and/or digital microelectronics, PCB design, signal processing and programming. Show details
Keywords
Microelectronics, CMOS, circuit design, electronics, PCB, signal processing, neural interface.
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Semester Project , Internship , Bachelor Thesis , Master Thesis
Description
Contact Details
Published since: 2024-01-17
Earliest start: 2022-01-03
Organization: Bio Engineering Laboratory
Hosts: Cardes Fernando
Topics: Engineering and Technology
Software development for neural interfaces
The student will be involved in the development of software applications for in-vitro neural interfaces. These applications include tasks such as visualizing neural recordings, real-time signal processing, and interfacing with our CMOS-based systems. Show details
Keywords
Software development, Python, C++, Linux, Embedded systems, FPGA, Neural interfaces.
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Semester Project , Internship , Bachelor Thesis , Master Thesis
Description
Contact Details
Published since: 2024-01-17
Earliest start: 2023-09-01
Organization: Bio Engineering Laboratory
Hosts: Cardes Fernando
Topics: Information, Computing and Communication Sciences , Engineering and Technology
Microfabrication / nanofabrication of 3D nanostructures on micro-electrode arrays for high coupling neuron-chip interface
The Bio Engineering Lab (ETH Zurich, based in Basel) has a long tradition of pioneering densely-integrated CMOS devices capable of electrically interfacing with an in vitro neuronal systems (e.g. cultures, brain slices etc.). This position invites you to work on the fabrication methods and/or characterization of novel 3D structures that promote a strong coupling between the two heterogeneous systems, namely CMOS sensor chips and in vitro neurons. Show details
Keywords
microfabrication, nanofabrication, micro-electrode arrays, electrophysiology, neural interface, cell cultures, CMOS
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Semester Project , Master Thesis
Description
Contact Details
Published since: 2024-01-08
Earliest start: 2024-01-31
Latest end: 2024-09-30
Organization: Bio Engineering Laboratory
Hosts: Bui Cat
Topics: Engineering and Technology
Microfabrication and characterization of electrodes for neural interfaces
The focus of this project is on the intricate fabrication of microelectrodes for advanced neural interfaces in a cutting-edge cleanroom environment. Our research aims to develop high-resolution neural probes utilizing state-of-the-art microfabrication techniques. Show details
Keywords
Microfabrication; Cleanroom; Neural Interfaces; Microelectrode Arrays; Biomedical Devices; Nanotechnology; Electrochemical Deposition; Neurotechnology; Semiconductor Processing; Bioengineering.
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Semester Project , Master Thesis
Description
Contact Details
Published since: 2023-11-22
Earliest start: 2023-12-01
Organization: Bio Engineering Laboratory
Hosts: Cardes Fernando
Topics: Engineering and Technology